Released 15 June 1948, A&C Meet Frankenstein was the first of the duo’s seven A&C Meet… pictures. It made over $3 million at the box office, and remains one of their best-known and most popular films.
In London, Lawrence Talbot (Lon Chaney, Jr.) places an urgent call to a Florida railway station’s baggage department, where Wilbur Gray (Lou) and Chick Young (Bud) work. He asks if there are two crates addressed to McDougal House of Horrors, and says under no circumstances are the crates to be delivered until he arrives.
During this phonecall, Talbot transforms into the Wolfman, and rips up his room. Wilbur thinks he’s put his dog on the line, and hangs up in disgust.
McDougal then arrives, demanding his crates. Wilbur doesn’t want to obey him, but McDougal insists. While Wilbur and Chick fetch the crates, he tells Wilbur’s girlfriend Sandra the crates contain Count Dracula and Frankenstein’s monster. They’ve been insured for $20,000.
McDougal is furious at Wilbur’s mishandling of the crates, and orders him to take them to his House of Horrors so an insurance agent can inspect them. If Wilbur damages them, he intends to collect that $20,000.
While Wilbur opens the first crate, Chick answers a call from McDougal and assures him everything’s alright. Chick is quite bemused by Wilbur’s fear of the creatures in the House of Horrors, and even more so by Wilbur’s belief that the coffin inside the crate contains the real Dracula.
While Wilbur is reading a card about the legend of Dracula, he hears odd noises. The next time Chick is out, Wilbur sees the coffin opening. Chick thinks Wilbur is being ridiculous and wasting time, since these creepy goings-on only happen when Chick isn’t there.
Conveniently, Dracula (Béla Lugosi) has left his coffin and is lurking in the shadows by the time Chick investigates. Chick laughs while reading the card for the next crate, about Frankenstein’s monster, but Wilbur takes it very seriously.
While they’re opening this crate, Dracula gets back into his coffin. Wilbur is so freaked out to see Frankenstein’s monster (Glenn Strange), he bumps into a guillotine and causes a dummy to get beheaded.
The next time Chick is out, Dracula puts Wilbur under his spell, and then brings Frankenstein’s monster to life. By the time McDougal arrives with the insurance man, both monsters are gone. McDougal has Wilbur and Chick arrested.
Dracula compels Frankenstein’s monster to his castle, where we learn Sandra is in cahoots with him. He insists she call him Dr. Lajos, to avoid suspicion.
Dracula doesn’t want to repeat Dr. Frankenstein’s mistake by giving the monster a bad brain. He wants the monster to have no intellect or will of his own, so he’ll bend to his master’s will. Sandra has just the brain in mind—Wilbur’s.
Talbot comes to see Wilbur and Chick, who’ve been bailed out of jail. He’s horrorstruck the crates were delivered before he arrived, and says he’s been tracking Dracula from Europe. Talbot believes Dracula wants to bring Frankenstein’s monster to life.
Talbot demands Wilbur lock him into his room, and not let him out no matter what, since the Moon will soon be full. Of course, Talbot has forgotten his suitcase, and Wilbur helpfully delivers it. He’s changed into the Wolfman by the time Wilbur gets there, but avoids detection the entire time.
In the morning, Wilbur and Chick meet undercover investigator Joan Raymond, who reveals she, not Sandra, paid their bail. Wilbur asks her to be his date to that night’s masquerade ball, to which he’s also taking Sandra.
When Wilbur and Chick unlock Talbot, they find him in a very disheveled state. They laugh off his story about being bitten by a werewolf, but he insists he’s completely serious, and that they have to find the missing monsters.
Sandra is upset Wilbur has come to Dracula’s castle with Chick and Joan, since she wanted him to come alone. While the ladies are changing into their costumes, Talbot calls and warns Wilbur he may be in the house of Dracula. Talbot also wants them to search the place.
Their search yields a lot of extremely creepy, unexpected things, among them the monsters. Yet again, only Wilbur encounters them, and Chick is convinced he’s making things up.
The plot thickens when Dracula meets Wilbur, and Sandra discovers Joan is from the insurance company.